Open Access 
              
Copyright: The authors. This article is an open access 
article licensed under the terms of the Creative Commons Attribution License 
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, 
distribution and reproduction in any medium, provided the work is properly 
cited.
              
              
              
              
              Research
              
              
              
              4.   
                  
                  
                              
                              Plasma biochemical indices at various stages of 
                              infection with a field isolate of Eimeria 
                              tenella in broiler chicken - 
                              Dipak Kumar Mondal, Saibal Chattopadhyay, 
                              Subhasish Batabyal, Asit Kumar Bera,Debasis 
                              Bhattacharya
                              Vet World. 2011; 4(9): 404-409
               
              
              
              doi: 10.5455/vetworld.2011.404-409
              
              
               
              
              
              
   
 
              
               
               
               
              
              
              Abstract
              
                              
              
              
              Coccidiosis has a major impact on poultry industry as it affects 
              broiler and layer birds of all age groups. Caecal
              
              coccidiosis, caused by 
              
              Eimeria tenella 
              is a very devastating 
              enteric disease in broiler, which involves huge economic loss.
              
              In 
              present study, 
              experimental infective dose of 
              
              
              Eimeria tenella isolated from field was determined 
              in broiler chicken and subsequent alterations in different plasma 
              biochemical constituents were evaluated at interval of 5th, 
              7th and 9th day of post inoculation (PI) with the selected dose of 
              20000-25000 sporulated oocyst per bird. The dose was selected 
              based on titration. A significant increase in plasma glucose, 
              total cholesterol level and aspartate aminotransferase (AST) 
              activity were observed where as a significant decrease in the 
              level of total plasma protein, albumin, globulin, triglyceride and 
              alanine aminotransferase (ALT) activity were evident during 
              infection 
              
              Highest degree of infection. was found on 7th
              
              day 
              PI. Onward 9th 
              day of PI onward clinical recovery was confirmed on the basis of 
              pathognomonic 
              
              caecal lesion score, clinical signs and symptoms.
              
              Keywords: 
              Coccidiosis, Eimeria tenella; Post Inoculation, Oocyst, Poultry
.